Effect of intraluminal thrombus on growth rate of abdominal aortic aneurysms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00070953" target="_blank" >RIV/00159816:_____/19:00070953 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/19:00110190

Result on the web

<a href="https://www.minervamedica.it/en/journals/international-angiology/article.php?cod=R34Y2019N01A0039" target="_blank" >https://www.minervamedica.it/en/journals/international-angiology/article.php?cod=R34Y2019N01A0039</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.23736/S0392-9590.18.04006-3" target="_blank" >10.23736/S0392-9590.18.04006-3</a>

Result language

angličtina

Original language name

Effect of intraluminal thrombus on growth rate of abdominal aortic aneurysms

Original language description

Background: Abdominal aortic aneurysm (AAA) includes a variety of morphologies with changing properties. Growth rate is one of the most important factors directly linked to the risk of rupture. Intraluminal thrombus (ILT) covering aortic wall is found in the majority of AAAs. Yet, its role in biomechanical processes in AAA remains unclear. From one point of view ILT can serve as protective factor in reducing wall stress of AAA and thus slow down the growth. Modern concept of multilayered ILT proved active inflammatory processes inside, that can significantly affect the quality of the wall and thus lead to a higher growth rate and higher risk of rupture. The goal of this study was to analyze the effect of ILT on growth rate of AAA and support one of these theories. Methods: Retrospective study of computed tomography angiography scans of AAA of 26 patients was performed. Forty pairs of consecutive scans have been analyzed. Periods between two scans varied. Maximal infrarenal diameter of AAA and size of ILT were measured. AAAs were split into 4 groups according to their initial diameter. Growth rate was calculated for each AAA and linked to the relative size of ILT. These values were statistically evaluated. Results: Negative correlation between relative size of ILT and growth rate was found (P=0.042062). This significant result proved that thicker thrombus slowed down the growth of AAA and vice versa, smaller relative size of ILT was linked to higher growth rate. Conclusions: This finding shows importance of ILT as one of the key factors influencing biomechanical processes inside an AAA. Results of this study may contribute to future researches of this topic.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Angiology

ISSN

0392-9590

e-ISSN

—

Volume of the periodical

38

Issue of the periodical within the volume

1

Country of publishing house

IT - ITALY

Number of pages

7

Pages from-to

39-45

UT code for WoS article

000461074100006

EID of the result in the Scopus database

—