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The impact of Intra-luminal Thrombus failure on the mechanical stress in the wall of Abdominal Aortic Aneurysms

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F11%3APU93036" target="_blank" >RIV/00216305:26210/11:PU93036 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The impact of Intra-luminal Thrombus failure on the mechanical stress in the wall of Abdominal Aortic Aneurysms

  • Original language description

    The role of the Intra-luminal Thrombus (ILT) in Abdominal Aortic Aneurysm (AAA) rupture is controversial and it is still not clear if an ILT increases or decreases AAA rupture risk. Specifically, signs of bleeding in the ILT are thought to increase AAA rupture risk. In order to further investigate this hypothesis, intact AAAs (n=4) with clear signs of ILT rupture in Computer Tomography Angiography (CT-A) images were investigated. To this end two cases were investigated: an ILT failure extracted directlyfrom the CT-A data and a hypothetical ILT fissure connecting the lumen with the underlying aneurysm wall. Wall stress distributions were predicted based on the detailed Finite Element (FE) models. The study showed that the ILT rupture, as extracted fromthe CT-A data, can increase the mechanical stress in the underlying wall by up to 30%. The largest impact on the wall stress was observed if the ILT failure reaches the aneurysm wall or if it involves large parts of the ILT. In contrast,

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA106%2F09%2F1732" target="_blank" >GA106/09/1732: MULTISCALE MODELLING OF BEHAVIOUR OF HYPERELASTIC ANISOTROPIC MATERIALS</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

  • ISSN

    1078-5884

  • e-ISSN

  • Volume of the periodical

    41

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    467-473

  • UT code for WoS article

  • EID of the result in the Scopus database