Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00071026" target="_blank" >RIV/00159816:_____/19:00071026 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/19:00110199

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S1388245719301208" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S1388245719301208</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clinph.2019.03.026" target="_blank" >10.1016/j.clinph.2019.03.026</a>

Result language

angličtina

Original language name

Hippocampal high frequency oscillations in unilateral and bilateral mesial temporal lobe epilepsy

Original language description

Objective: The main aim of this study was to investigate the potential differences in terms of interictal high frequency oscillations (HFOs) between both hippocampi in unilateral (U-MTLE) and bilateral mesial temporal lobe epilepsy (B-MTLE). Methods: Sixteen patients with MTLE underwent bilateral hippocampal depth electrode implantation as part of epilepsy surgery evaluation. Interictal HFOs were detected automatically. The analyses entail comparisons of the rates and spatial distributions of ripples and fast ripples (FR) in hippocampi and amygdalae, with respect to the eventual finding of hippocampal sclerosis (HS). Results: In U-MTLE, higher ripple and FR rates were found in the hippocampi ipsilateral to the seizure onset than in the contralateral hippocampi. Non-epileptic hippocampi in U-MTLE were distinguished by significantly lower ripple rate than in the remaining analyzed hippocampi. There were not differences between the hippocampi in B-MTLE. In the hippocampi with proven HS, higher FR rates were observed in the ventral than in the dorsal parts. Conclusions: Non-epileptic hippocampi in U-MTLE demonstrated significantly lower ripple rates than those epileptic in U-MTLE and B-MTLE. Significance: Low interictal HFO occurrence might be considered as a marker of the non-epileptic hippocampi in MTLE. (C) 2019 Published by Elsevier B.V. on behalf of International Federation of Clinical Neurophysiology.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Neurophysiology

ISSN

1388-2457

e-ISSN

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Volume of the periodical

130

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

1151-1159

UT code for WoS article

000469338500008

EID of the result in the Scopus database

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