Anterior thalamic deep brain stimulation in epilepsy and persistent psychiatric side effects following discontinuation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00071777" target="_blank" >RIV/00159816:_____/19:00071777 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/19:00108623

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S2589986419301297?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2589986419301297?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ebr.2019.100344" target="_blank" >10.1016/j.ebr.2019.100344</a>

Result language

angličtina

Original language name

Anterior thalamic deep brain stimulation in epilepsy and persistent psychiatric side effects following discontinuation

Original language description

We report a case of a patient with drug-resistant epilepsy treated with deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS). The patient developed psychiatric side effects (PSEs), namely irritability, hostility, aggressiveness, and paranoia, after implantation and stimulation initiation. The stimulation was discontinued and the PSEs were mitigated, but the patient did not return to her pre-implantation state, as documented by repeated psychiatric reports and hospitalizations. To our knowledge, this is the first report of a patient who developed long-term PSEs that did not disappear after stimulation discontinuation. We suppose that ANT-DBS caused a persistent perturbation of the thalamic neuronal networks that are responsible for long-term PSEs. (C) 2019 Published by Elsevier Inc.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

<a href="/en/project/NV19-04-00343" target="_blank" >NV19-04-00343: Prediction of Stimulation Efficacy in Epilepsy (PRESEnCE)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epilepsy &amp; Behavior Reports

ISSN

2589-9864

e-ISSN

—

Volume of the periodical

12

Issue of the periodical within the volume

2019

Country of publishing house

US - UNITED STATES

Number of pages

3

Pages from-to

100344

UT code for WoS article

000566534900006

EID of the result in the Scopus database

2-s2.0-85081058842