Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F21%3A00119502" target="_blank" >RIV/00216224:14740/21:00119502 - isvavai.cz</a>
Alternative codes found
RIV/68081731:_____/21:00544467 RIV/00159816:_____/21:00074743
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1111/epi.16883" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/epi.16883</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/epi.16883" target="_blank" >10.1111/epi.16883</a>

Result language
angličtina
Original language name
Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus
Original language description
We hypothesized that local/regional properties of stimulated structure/circuitry contribute to the effect of deep brain stimulation (DBS). We analyzed intracerebral electroencephalographic (EEG) recordings from externalized DBS electrodes targeted bilaterally in the anterior nuclei of the thalamus (ANT) in 12 patients (six responders, six nonresponders) with more than 1 year of follow-up care. In the bipolar local field potentials of the EEG, spectral power (PW) and power spectral entropy (PSE) were calculated in the passbands 1-4, 4-8, 8-12, 12-20, 20-45, 65-80, 80-200 and 200-500 Hz. The most significant differences between responders and nonresponders were observed in the BRIDGE area (bipolar recordings with one contact within the ANT and the second contact in adjacent tissue). In responders, PW was significantly decreased in the frequency bands of 65-80, 80-200, and 200-500 Hz (p < .05); PSE was significantly increased in all frequency bands (p < .05) except for 200-500 Hz (p = .06). The local EEG characteristics of ANT recorded after implantation may play a significant role in DBS response prediction.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30210 - Clinical neurology

Project
<a href="/en/project/GA21-25953S" target="_blank" >GA21-25953S: Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)