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Xeno- and feeder-free derivation of two sex-discordant sibling lines of human embryonic stem cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074985" target="_blank" >RIV/00159816:_____/21:00074985 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/21:00120158

  • Result on the web

    <a href="https://reader.elsevier.com/reader/sd/pii/S1873506121004219?token=CC069092E1ABA87DF85E88C7D8D0DB6B9F5C3BF16F7BA65A0593A4DF305210B0C6EA8E6DACDB5AE8322939476E2B7B37&originRegion=eu-west-1&originCreation=20220112103311" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1873506121004219?token=CC069092E1ABA87DF85E88C7D8D0DB6B9F5C3BF16F7BA65A0593A4DF305210B0C6EA8E6DACDB5AE8322939476E2B7B37&originRegion=eu-west-1&originCreation=20220112103311</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.scr.2021.102574" target="_blank" >10.1016/j.scr.2021.102574</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Xeno- and feeder-free derivation of two sex-discordant sibling lines of human embryonic stem cells

  • Original language description

    Human embryonic stem cells (hESCs) represent a virtually unlimited source of cells suitable for a variety of biomedical applications. However, a diminishing allogeneic background and undefined culture conditions are essential for developing robust and replicable protocols for differentiation experiments, disease modeling, and drug testing. Therefore, here we report the generation of the two sex-discordant sibling hESC lines, MUNIe008-A and MUNIe009-A, using the mechanical biopsy of vitrified-thawed embryos under xeno-and feeder-free conditions. The presented approach is applicable for deriving high-quality clinical-grade hESC lines for cell replacement therapies.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Stem Cell Research

  • ISSN

    1873-5061

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    December

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    4

  • Pages from-to

  • UT code for WoS article

    000712140900005

  • EID of the result in the Scopus database