Bidirectional Association Between Sleep and Brain Atrophy in Aging

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074986" target="_blank" >RIV/00159816:_____/21:00074986 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/21:10437732 RIV/65269705:_____/21:00074986 RIV/00064165:_____/21:10437732 RIV/00216224:14110/21:00123751
Result on the web
<a href="https://www.frontiersin.org/articles/10.3389/fnagi.2021.726662/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fnagi.2021.726662/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fnagi.2021.726662" target="_blank" >10.3389/fnagi.2021.726662</a>

Result language
angličtina
Original language name
Bidirectional Association Between Sleep and Brain Atrophy in Aging
Original language description
Human brain aging is characterized by the gradual deterioration of its function and structure, affected by the interplay of a multitude of causal factors. The sleep, a periodically repeating state of reversible unconsciousness characterized by distinct electrical brain activity, is crucial for maintaining brain homeostasis. Indeed, insufficient sleep was associated with accelerated brain atrophy and impaired brain functional connectivity. Concurrently, alteration of sleep-related transient electrical events in senescence was correlated with structural and functional deterioration of brain regions responsible for their generation, implying the interconnectedness of sleep and brain structure. This review discusses currently available data on the link between human brain aging and sleep derived from various neuroimaging and neurophysiological methods. We advocate the notion of a mutual relationship between the sleep structure and age-related alterations of functional and structural brain integrity, pointing out the position of high-quality sleep as a potent preventive factor of early brain aging and neurodegeneration. However, further studies are needed to reveal the causality of the relationship between sleep and brain aging.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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