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Salivary and serum neopterin and interleukin 6 as biomarkers in patients with oral and oropharyngeal squamous cell carcinoma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F22%3A00077779" target="_blank" >RIV/00159816:_____/22:00077779 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/22:10157611 RIV/61989592:15110/22:73617237

  • Result on the web

    <a href="https://www.degruyter.com/document/doi/10.1515/pteridines-2022-0045/html" target="_blank" >https://www.degruyter.com/document/doi/10.1515/pteridines-2022-0045/html</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1515/pteridines-2022-0045" target="_blank" >10.1515/pteridines-2022-0045</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Salivary and serum neopterin and interleukin 6 as biomarkers in patients with oral and oropharyngeal squamous cell carcinoma

  • Original language description

    Because of an increasing incidence of malignant tumours of the head and neck there is an unmet medical need for early diagnosis of the primary disease or precancerous lesions, and timely detection of recurrence by simple non-invasive tests. The analysis of biomarkers in body fluids may be appropriate for this goal. In this review, we compare the data on utilization of neopterin and interleukin-6 (IL-6) measurements in saliva and plasma/serum of patients with oral and oropharyngeal squamous cell carcinoma, indicating the suitability of using saliva as a diagnostic matrix in head and neck cancers on behalf of close anatomical proximity and a potential to study the tumour microenvironment. Salivary neopterin and IL-6 are potential biomarkers of head and neck cancer suitable not only for early diagnosis, but also for monitoring of treatment results and detection of the disease recurrence.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10600 - Biological sciences

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    PTERIDINES

  • ISSN

    0933-4807

  • e-ISSN

    2195-4720

  • Volume of the periodical

    33

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    9

  • Pages from-to

    78-86

  • UT code for WoS article

    000907659800001

  • EID of the result in the Scopus database