Prognostic Properties of the GOLD 2023 Classification System

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00077999" target="_blank" >RIV/00159816:_____/23:00077999 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/23:00130744 RIV/61988987:17110/23:A2402KZU RIV/00216208:11150/23:10464816 RIV/61989592:15110/23:73619042 and 2 more

Result on the web

<a href="https://www.dovepress.com/getfile.php?fileID=89116" target="_blank" >https://www.dovepress.com/getfile.php?fileID=89116</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/COPD.S410372" target="_blank" >10.2147/COPD.S410372</a>

Result language

angličtina

Original language name

Prognostic Properties of the GOLD 2023 Classification System

Original language description

Introduction: Recently, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published an update on the Global Strategy for Prevention, Diagnosis and Management of COPD, introducing a new classification of chronic obstructive pulmonary disease (COPD). Our aim was to assess the prognostic value of the new GOLD classification system in comparison with the previous GOLD classification systems (GOLD stages I-IV and GOLD groups A-D) and the BODE index.Methods: We used the data of 784 patients with COPD from the Czech Multicenter Research Database of COPD. Patient survival was analyzed with the use of Kaplan-Meier estimate and Cox model of proportional risks. ROC analysis and area under curve (AUC) were used for comparison of GOLD classifications and BODE index. The analyses were performed with the use of software R (version 4.2.0).Results: We analyzed data of 782 patients with complete data on GOLD classifications. The study population comprised 72.9% of men, 89.1% current or former smokers, with a mean age of 66.6 years, a mean BMI of 27.4 and a mean FEV1 44.9% of predicted. Probability of 5-year survival differed by GOLD classification. Application of the 2023 GOLD classification showed increased risk of death in group B (HR 1.82, 95% CI 1.14-2.92; p = 0.013) and in group E (HR 2.48, 95% CI 1.54-3.99; p&lt;0.001). The ROC analysis showed that the overall prognostic value of the 2023 GOLD classification was similarly weak to previous A-D GOLD classification schemes (AUCs 0.557-0.576) and was lower compared to the GOLD 1-4 system (AUC 0.614) and even lower when compared to the BODE index (AUC 0.715).Conclusion: We concluded that the new GOLD classification system has poor prognostic properties and that specific prediction tools (eg, the BODE index) should be used for mortality risk assessment.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30203 - Respiratory systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Chronic Obstructive Pulmonary Disease

ISSN

1178-2005

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

2023

Country of publishing house

NZ - NEW ZEALAND

Number of pages

7

Pages from-to

661-667

UT code for WoS article

000975875800001

EID of the result in the Scopus database

2-s2.0-85159082962