Brain Areas Predisposing to the Stroke-Related Epilepsy Development
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00078776" target="_blank" >RIV/00159816:_____/23:00078776 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/23:10469150 RIV/00179906:_____/23:10469150 RIV/00216224:14110/23:00134674
Result on the web
<a href="https://www.hindawi.com/journals/ans/2023/1439121/" target="_blank" >https://www.hindawi.com/journals/ans/2023/1439121/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2023/1439121" target="_blank" >10.1155/2023/1439121</a>
Alternative languages
Result language
angličtina
Original language name
Brain Areas Predisposing to the Stroke-Related Epilepsy Development
Original language description
Background. Stroke-related epilepsy (STRE) represents a significant health problem. We focused on identifying brain areas, which involvement in ischemia predisposes a patient to STRE development. Methods. We retrospectively identified a group of patients with STRE consisting of 33 subjects. Subsequently, age-, sex-, and territory-matched controls who underwent stroke but did not develop STRE (control group (CG)) were identified. The CG was composed of 37 patients. The total ischemia volume and distribution of ischemic changes were compared between STRE and CG. We also analyzed multivariate statistics to identify independent variables predisposing to STRE development. Results. The patients with STRE exhibited a bigger volume of ischemia than CG (average volume of ischemia in STRE 60.8 cm3, in CG 42.4 cm3, p=0.029). When comparing STRE and CG, there were differences in the distribution of ischemic changes in the temporal lobe (transverse (Heschl's) temporal gyri, superior temporal gyrus, and middle temporal gyrus) and parietooccipital region (postcentral gyrus, supramarginal gyrus, angular gyrus, parietal operculum, lingual gyrus, and superior occipital gyrus). The involvement of transverse temporal (Heschl's) gyri (p=0.0222, odds ratio 30.0767), age (p=0.0110, odds ratio 1.0745), and SeLECT score (p=0.0480, odds ratio 1.8682) were identified as independent predictors for STRE development. Conclusion. The higher volume of ischemia correlates with a higher risk of STRE development. Some areas, particularly in the temporal and parietal neocortex, predispose the brain to generate epilepsy after the stroke.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
<a href="/en/project/NU21-04-00254" target="_blank" >NU21-04-00254: Detection of seizure onset zone in multi-lesional epilepsies using multimodal imaging methods</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta neurologica Scandinavica
ISSN
0001-6314
e-ISSN
1600-0404
Volume of the periodical
2023
Issue of the periodical within the volume
AUG 25
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
1439121
UT code for WoS article
001057498800001
EID of the result in the Scopus database
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