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ChannelsDB 2.0: a comprehensive database of protein tunnels and pores in AlphaFold era

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00079726" target="_blank" >RIV/00159816:_____/24:00079726 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14310/24:00135278 RIV/61989592:15310/24:73620930

  • Result on the web

    <a href="https://academic.oup.com/nar/article/52/D1/D413/7416806" target="_blank" >https://academic.oup.com/nar/article/52/D1/D413/7416806</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1093/nar/gkad1012" target="_blank" >10.1093/nar/gkad1012</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    ChannelsDB 2.0: a comprehensive database of protein tunnels and pores in AlphaFold era

  • Original language description

    ChannelsDB 2.0 is an updated database providing structural information about the position, geometry and physicochemical properties of protein channels-tunnels and pores-within deposited biomacromolecular structures from PDB and AlphaFoldDB databases. The newly deposited information originated from several sources. Firstly, we included data calculated using a popular CAVER tool to complement the data obtained using original MOLE tool for detection and analysis of protein tunnels and pores. Secondly, we added tunnels starting from cofactors within the AlphaFill database to enlarge the scope of the database to protein models based on Uniprot. This has enlarged available channel annotations similar to 4.6 times as of 1 September 2023. The database stores information about geometrical features, e.g. length and radius, and physico-chemical properties based on channel-lining amino acids. The stored data are interlinked with the available UniProt mutation annotation data. ChannelsDB 2.0 provides an excellent resource for deep analysis of the role of biomacromolecular tunnels and pores. The database is available free of charge: https:////channelsdb2.biodata.ceitec.cz. Graphical Abstract

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nucleic Acids Research

  • ISSN

    0305-1048

  • e-ISSN

    1362-4962

  • Volume of the periodical

    52

  • Issue of the periodical within the volume

    D1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    "D413"-"D418"

  • UT code for WoS article

    001101754200001

  • EID of the result in the Scopus database