ModCRElib

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F25%3A00082511" target="_blank" >RIV/00159816:_____/25:00082511 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

ModCRElib

Original language description

The ModCRElib package provides various tools for the analysis and modeling of Transcription Factor (TF)-DNA and regulatory complex inter-protein interactions. It takes structural information on these interactions to predict TF binding motifs, generate binding profiles along DNA sequences that score the affinity, predict TF binding sites, and model the structure of higher-order regulatory complexes. It is capable of working with a variety of input data formats and sources. The user may follow the analysis pipeline as outlined in the documentation, or utilize any of the multiple functionalities in an isolated manner. The package leverages the service offered by the ModCRE server, enabling users to apply its tools in an unrestricted and customizable manner. Examples of ModCRElib use includes: (i) TF binding affinity prediction, (ii) TF binding aggregation, (iii) prediction of TF binding sites along target DNA sequences, (iv) modelling TF bound to their predicted binding sites, and (v) the generation of statistical potential derived scoring profiles of TF interacting with DNA.

Czech name

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Czech description

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Type

R - Software

CEP classification

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OECD FORD branch

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project

<a href="/en/project/LM2023055" target="_blank" >LM2023055: Czech National Infrastructure for Biological Data</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Internal product ID

2-SW-2025

Technical parameters

Doposud je využíváno interně k výzkumným účelům.

Economical parameters

V budoucnu je plánována nabídka potencionálním partnerům z komerční sféry.

Owner IČO

00159816

Owner name

Fakultní nemocnice u sv. Anny v Brně