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Genotyping of varicella-zoster virus (VZV) wild-type strains isolated in the Czech Republic

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10107427" target="_blank" >RIV/00179906:_____/11:10107427 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/11:10107427

  • Result on the web

    <a href="http://biomed.papers.upol.cz/pdfs/bio/2011/04/11.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2011/04/11.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2011.056" target="_blank" >10.5507/bp.2011.056</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Genotyping of varicella-zoster virus (VZV) wild-type strains isolated in the Czech Republic

  • Original language description

    A total of 273 clinical samples were obtained from patients exhibiting symptoms of varicella zoster virus (VZV) infection manifested as chickenpox or herpes zoster (HZ) treated in the Faculty Hospital of Charles University, Medical School in Hradec Kralove, Czech Republic Characterization of individual VZV strains was performed utilizing restriction fragment length polymorphisms (RFLPs), PCR and sequencing. Single nucleotide polymorphisms (SNP) in the open reading frames (ORF) 21, 22 and 50 were used toidentify individual VZV strains. All clinical isolates (97 from varicella, 176 from herpes zoster) were VZV positive wild-type strains. Sequencing analysis showed that 89 isolates were of the European E1 genotype, 180 were of the European E2 genotype and 2 were identified as the Mosaic M1 strain. In addition, two unusual genotypes were identified, both representing a combination of E1 and M2 strain specific SNPs. Our prospective VZV genotyping study is the first one monitoring the situa

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, CzechoSK

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    155

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    379-384

  • UT code for WoS article

    000299697000012

  • EID of the result in the Scopus database