The number of immunoregulatory T cells is increased in patients with psoriasis after Goeckerman therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10125393" target="_blank" >RIV/00179906:_____/12:10125393 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/12:10125393

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The number of immunoregulatory T cells is increased in patients with psoriasis after Goeckerman therapy

Original language description

Regulatory T cells (Treg) are a specialized subpopulation of T cells that act to suppress inadequate immune response. Psoriasis is recognized as a T cell driven immune-mediated systemic inflammatory disease wit skin manifestation. Effective therapeuticalapproach to treat psoriasis is Goeckerman therapy (GT). The aim of this study was to compare the number of Treg in the peripheral blood of 27 psoriatic patients and 19 controls and to evaluate the influence of GT on Treg population in peripheral blood of patients with psoriasis. There was no significant difference in the relative number of Treg cells in the peripheral blood of healthy blood donors and patients with psoriasis before initiation of GT (P = 0.2668). In contrary, the relative number of Tregcells in peripheral blood of patients with psoriasis after GT was significantly higher than those found in healthy blood donors (P = 0.0019). Moreover, the relative number of Treg is significantly increased in psoriatic patients after Go

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Kralove

ISSN

1211-4286

e-ISSN

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Volume of the periodical

55

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

91-95

UT code for WoS article

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EID of the result in the Scopus database

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