Topically-used gentamicin attached to nanofibre MDOC compared with Garamycin Schwamm in an acute wound infection model. An experimental study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10133956" target="_blank" >RIV/00179906:_____/12:10133956 - isvavai.cz</a>

Alternative codes found

RIV/60162694:G44__/12:43874266

Result on the web

<a href="http://mmsl.cz/viCMS/soubory/pdf/MMSL_2012_1_2_WWW.pdf" target="_blank" >http://mmsl.cz/viCMS/soubory/pdf/MMSL_2012_1_2_WWW.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Topically-used gentamicin attached to nanofibre MDOC compared with Garamycin Schwamm in an acute wound infection model. An experimental study

Original language description

The aim of this study was to examine the effect of topically-used gentamicin attached to a biodegradable carrier, formed by micro-dispersed oxidised cellulose (MDOC) in nanobire form, in acute wound infection treatment and to compare it with Garamycin Schvamm. Twelve domestic swines were used in a model of a full-thickness infected dermal wound. The effectiveness of both materials in wound infections caused by Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli was tested. The effectiveness of both gentamicin with MDOC and Garamycin Schwamm was comparable in Pseudomonas aeruginosa and Escherichia coli infections according to microbiological cultures findings. With Staphylococcus aureus infections there was a higher percent of negative cultures when MDOC with gentamicin was administered, but without statistical significance (p=0.069). When macroscopically assesed, 100 % of infected wounds treated by gentamicin attached to MDOC were without signs of local infection compare

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Vojenské zdravotnické listy

ISSN

0372-7025

e-ISSN

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Volume of the periodical

81

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

9-15

UT code for WoS article

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EID of the result in the Scopus database

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