Nanofiber micro-dispersed oxidized cellulose as a carrier for topical antimicrobials: first experience

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F10%3A00002347" target="_blank" >RIV/60162694:G44__/10:00002347 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Nanofiber micro-dispersed oxidized cellulose as a carrier for topical antimicrobials: first experience

Original language description

Micro-dispersed oxidized cellulose (MDOC) might be helpful for introduction of an antimicrobial drug. The aim of the experimental study was to examine the effect of topically apllied gentamicin attached to MDOC in micro- and nanofiber form for treatmentof acute wound inefctions. A model of a full-thickness infected dermal wound was created in 12 female domestic pigs and the effectiveness of topical gentamicin with MDOC in acute wound infections caused by Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli was tested. Based on macroscopic assessment and culture findings results we proved good effectiveness of MDOC with a sufficient concentration of an antibiotic in the treatment of full-thickness wound infections.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Surgical Infections

ISSN

1096-2964

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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