In vitro antimicrobial activity of light-activated phthalocyanines

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F13%3A10189431" target="_blank" >RIV/00179906:_____/13:10189431 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/13:10189431

Result on the web

<a href="http://dx.doi.org/10.2478/s11535-013-0118-0" target="_blank" >http://dx.doi.org/10.2478/s11535-013-0118-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/s11535-013-0118-0" target="_blank" >10.2478/s11535-013-0118-0</a>

Result language

angličtina

Original language name

In vitro antimicrobial activity of light-activated phthalocyanines

Original language description

Background: Photodynamic antimicrobial therapy (PACT) is proposed as a topical, non-invasive approach suitable for treatment of locally occurring infection. Research of photosensitizers, (PS) as well as their development, is aimed at finding effective antimicrobial substances which would have a broad-spectrum potency. The aim of this paper is to evaluate the antimicrobial effect of phthalocyanine (Pc) derivatives. Methods: Fifteen different Pc compounds were investigated. Their photokilling activity wastested on Staphylococcus aureus, Escherichia coli and Candida albicans. After treating of microbial cells with Pc at the concentrations: 1 mg/l, 2 mg/l, 4 mg/l, 8 mg/l for 30 minutes, the cultures were irradiated with low-power laser light at a wavelength of 670 nm (20 J/cm2, 40 J/cm2). The effectiveness of photoinactivation was evaluated based on the decrease in number (log10) of viable bacteria. Results: Eight Pc compounds tested showed antibacterial effects against S. aureus, but onl

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

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Project

<a href="/en/project/2B06104" target="_blank" >2B06104: Photosensitizators in dentistry.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Central European Journal of Biology

ISSN

1895-104X

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

2

Country of publishing house

PL - POLAND

Number of pages

10

Pages from-to

168-177

UT code for WoS article

000312340500006

EID of the result in the Scopus database

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