Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10271915" target="_blank" >RIV/00179906:_____/14:10271915 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/14:43875096 RIV/00216208:11160/14:10271915
Result on the web
<a href="http://informahealthcare.com/doi/full/10.1517/14740338.2014.914168" target="_blank" >http://informahealthcare.com/doi/full/10.1517/14740338.2014.914168</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1517/14740338.2014.914168" target="_blank" >10.1517/14740338.2014.914168</a>
Alternative languages
Result language
angličtina
Original language name
Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine
Original language description
Introduction: Alzheimer's disease (AD) is a world-wide health problem with implications for an increasing number of people and countries. Populations suffering from AD financially strain the healthcare budgets of rich and poor countries alike. Moreover,no effective treatment is available and current drugs merely slow the progression of cognitive function deterioration and overall health status toward an inevitable end point. An increasing number of novel approaches have been tested in numerous clinicaltrials, but none of them has proved safe and effective for treating AD. Areas covered: This review summarizes all currently available compounds (donepezil, rivastigmine, galantamine, memantine) for the management of AD, concentrating on clinical aspectssuch as the mechanisms of action, pharmacokinetics, pharmacodynamics and clinical trials. This review also considers the mechanisms and side effects to provide perspective on current treatment options. Expert opinion: Novel approaches in
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
O - Projekt operacniho programu
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Expert Opinion on Drug Safety
ISSN
1474-0338
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
16
Pages from-to
759-774
UT code for WoS article
000336531500010
EID of the result in the Scopus database
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