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Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10271915" target="_blank" >RIV/00179906:_____/14:10271915 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/14:43875096 RIV/00216208:11160/14:10271915

  • Result on the web

    <a href="http://informahealthcare.com/doi/full/10.1517/14740338.2014.914168" target="_blank" >http://informahealthcare.com/doi/full/10.1517/14740338.2014.914168</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1517/14740338.2014.914168" target="_blank" >10.1517/14740338.2014.914168</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Outcomes of Alzheimer's disease therapy with acetylcholinesterase inhibitors and memantine

  • Original language description

    Introduction: Alzheimer's disease (AD) is a world-wide health problem with implications for an increasing number of people and countries. Populations suffering from AD financially strain the healthcare budgets of rich and poor countries alike. Moreover,no effective treatment is available and current drugs merely slow the progression of cognitive function deterioration and overall health status toward an inevitable end point. An increasing number of novel approaches have been tested in numerous clinicaltrials, but none of them has proved safe and effective for treating AD. Areas covered: This review summarizes all currently available compounds (donepezil, rivastigmine, galantamine, memantine) for the management of AD, concentrating on clinical aspectssuch as the mechanisms of action, pharmacokinetics, pharmacodynamics and clinical trials. This review also considers the mechanisms and side effects to provide perspective on current treatment options. Expert opinion: Novel approaches in

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    O - Projekt operacniho programu

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Expert Opinion on Drug Safety

  • ISSN

    1474-0338

  • e-ISSN

  • Volume of the periodical

    13

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    16

  • Pages from-to

    759-774

  • UT code for WoS article

    000336531500010

  • EID of the result in the Scopus database