Non-conventional compounds with potential therapeutic effects against Alzheimer's disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F19%3A50015593" target="_blank" >RIV/62690094:18470/19:50015593 - isvavai.cz</a>

Result on the web

<a href="https://www.tandfonline.com/doi/abs/10.1080/14737175.2019.1608823?journalCode=iern20" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/14737175.2019.1608823?journalCode=iern20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14737175.2019.1608823" target="_blank" >10.1080/14737175.2019.1608823</a>

Result language

angličtina

Original language name

Non-conventional compounds with potential therapeutic effects against Alzheimer's disease

Original language description

Introduction: Alzheimer&apos;s disease (AD) is the most common cause of dementia. Clinical progress in this pathogenesis field has drawn the attention of researchers, stimulating the investigation of novel treatment methods. Current therapies that deal with cholinesterase inhibitors and/or NMDA antagonists have shown a modest symptomatic potential, increasing the need for research into more efficient therapeutics. The goal of this review is to summarize the advances in, and the potential of, non-conventional therapies in AD treatment.Areas covered: In this review, the authors describe the current status of unusual therapies in AD treatment, evaluating the modern scientific contexts in which these therapies have been developed. The authors also highlight the usage of methylene blue, natural products, organophosphorus compounds, and Chinese medicine, along with the employment of nanotechnology.Expert opinion: The potential therapies discussed in this review will play increasingly important roles in the prevention and treatment of AD, improving disease management and quality of life for AD patients. Given the annual increasing number of people with dementia, it is crucial to invest in the search for novel therapeutics. In addition, more sophisticated diagnosis techniques are also essential, to allow for an early diagnosis and treatment.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EXPERT REVIEW OF NEUROTHERAPEUTICS

ISSN

1473-7175

e-ISSN

—

Volume of the periodical

19

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

21

Pages from-to

375-395

UT code for WoS article

000469048200002

EID of the result in the Scopus database

2-s2.0-85066146534