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Denosumab associated with bone density increase and clinical improvement in a long-term hemodialysis patient. Case report and review of the literature

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10281367" target="_blank" >RIV/00179906:_____/14:10281367 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/14:10281367

  • Result on the web

    <a href="http://orbis.lfhk.cuni.cz/Acta_Medica/2014/2014_30.pdf" target="_blank" >http://orbis.lfhk.cuni.cz/Acta_Medica/2014/2014_30.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Denosumab associated with bone density increase and clinical improvement in a long-term hemodialysis patient. Case report and review of the literature

  • Original language description

    Denosumab is a human monoclonal antibody representing a novel therapy of osteoporosis. Contrary to always other antiosteoporotic drugs, it is not contraindicated in advanced chronic kidney disease, as its pharmacokinetic does not differ from patients with normal kidney function. However, published case reports in chronic kidney disease (CKD) patients stopped the therapy after single dose because of hypocalcemia. We present a case of successful treatment of osteoporosis in a young hemodialysis patient with repeated denosumab doses.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11355" target="_blank" >NT11355: Optimising extracorporeal elimination strategy with regard to the calcium and phosphate metabolism disturbances (CKD-MBD) in patients with chronic kidney failure</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Medica (Hradec Králové)

  • ISSN

    1211-4286

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    4

  • Pages from-to

    30-33

  • UT code for WoS article

  • EID of the result in the Scopus database