Synthesis and Biological Activity of Quaternary Ammonium Salt-Type Agents Containing Cholesterol and Terpenes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10282167" target="_blank" >RIV/00179906:_____/14:10282167 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/14:10282167
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/ardp.201300407/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/ardp.201300407/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ardp.201300407" target="_blank" >10.1002/ardp.201300407</a>

Result language
angličtina
Original language name
Synthesis and Biological Activity of Quaternary Ammonium Salt-Type Agents Containing Cholesterol and Terpenes
Original language description
New quaternary ammonium salt-type compounds with lipophilic cholesterol and terpene moieties were synthesized. The compounds showed promising antibacterial and antimycobacterial activities. Those compounds containing the cholesterol moiety showed significant activity against Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus faecium. On the contrary, the antimycobacterial activity increased with the presence of the terpene unit in the molecule.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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