Anti-Outer membrane protein C and anti-glycoprotein 2 antibodies in inflammatory bowel disease and their association with complicated forms of Crohn's disease

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10285400" target="_blank" >RIV/00179906:_____/14:10285400 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10285400
Result on the web
<a href="http://www.biomedcentral.com/content/pdf/s12876-014-0190-1.pdf" target="_blank" >http://www.biomedcentral.com/content/pdf/s12876-014-0190-1.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12876-014-0190-1" target="_blank" >10.1186/s12876-014-0190-1</a>

Result language
angličtina
Original language name
Anti-Outer membrane protein C and anti-glycoprotein 2 antibodies in inflammatory bowel disease and their association with complicated forms of Crohn's disease
Original language description
Precise diagnostics of inflammatory bowel disease (IBD) and identification of potentially more aggressive phenotypes of Crohn's disease (CD) is urgently needed. The aim of our prospective study was to assess the relationship between serum anti-OmpC IgA (Outer membrane protein C), anti-GP2 (anti-glycoprotein 2) IgG and anti-GP2 IgA antibodies with IBD and their association with complicated forms of CD. The study included 86 patients with CD, 25 patients with UC and 45 controls, blood donors. In CD group,24/86 (28%) had B1 phenotype, 20/86 (23%) B2, 13/86 (15%) B3 and 29/86 (34%) B2 + B3. L1 involvement was present in 13/86 (15%), L2 in 13/86 (15%), L3 in 60/86 (70%). Serum anti-OmpC IgA, anti-GP2 IgG and IgA antibodies were investigated by means of ELISA. The data obtained were tested statistically by means of descriptive statistics, non-paired t-test, Mann-Whitney rank sum test, Spearman rank order correlation and Pearson product moment correlation using SigmaStat software. Anti-OmpC
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
—

Project
<a href="/en/project/NT13413" target="_blank" >NT13413: Determination of apoptosis in the bioptic samples taken from the colon</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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