POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10326817" target="_blank" >RIV/00179906:_____/16:10326817 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00089784 RIV/00216208:11150/16:10326817

Result on the web

<a href="https://www.dovepress.com/pope-study-rationale-and-methodology-of-a-study-to-phenotype-patients--peer-reviewed-fulltext-article-COPD" target="_blank" >https://www.dovepress.com/pope-study-rationale-and-methodology-of-a-study-to-phenotype-patients--peer-reviewed-fulltext-article-COPD</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/COPD.S88846" target="_blank" >10.2147/COPD.S88846</a>

Result language

angličtina

Original language name

POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe

Original language description

Chronic obstructive pulmonary disease (COPD) constitutes a major health challenge in Central and Eastern European (CEE) countries. However, clinical phenotypes, symptom load, and treatment habits of patients with COPD in CEE countries remain largely unknown. This paper provides a rationale for phenotyping COPD and describes the methodol-ogy of a large study in CEE. The POPE study is an international, multicenter, observational cross-sectional survey of patients with COPD in CEE. Participation in the study is offered to all consecutive outpatients with stable COPD in 84 centers across the CEE region if they fulfill the following criteria: age .40 years, smoking history $10 pack-years, a confirmed diagnosis of COPD with postbronchodilator FEV1/FVC ,0.7, and absence of COPD exacerbation $4 weeks. Medical history, risk factors for COPD, comorbidities, lung function parameters, symptoms, and phar-maceutical and nonpharmaceutical treatment are recorded. The POPE project is registered in ClinicalTrials.gov with the identifier NCT02119494. The primary aim of the POPE study was to phenotype patients with COPD in a real-life setting within CEE countries using predefined classifications. Secondary aims of the study included analysis of differences in symptoms, and diagnostic and therapeutic behavior in participating CEE countries. There is increasing acceptance toward a phenotype-driven therapeutic approach in COPD. The POPE study may contribute to reveal important information regarding phenotypes and therapy in real-life CEE.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FC - Pneumology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Chronic Obstructive Pulmonary Disease [online]

ISSN

1178-2005

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

2016

Country of publishing house

NZ - NEW ZEALAND

Number of pages

12

Pages from-to

611-622

UT code for WoS article

000372577600001

EID of the result in the Scopus database

2-s2.0-84961589420