Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F17%3A10366844" target="_blank" >RIV/00216208:11150/17:10366844 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00096971 RIV/00179906:_____/17:10366844

Result on the web

<a href="http://erj.ersjournals.com/content/erj/49/5/1601446.full.pdf" target="_blank" >http://erj.ersjournals.com/content/erj/49/5/1601446.full.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1183/13993003.01446-2016" target="_blank" >10.1183/13993003.01446-2016</a>

Result language

angličtina

Original language name

Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study

Original language description

Chronic obstructive pulmonary disease (COPD) represents a major health problem in Central and Eastern European (CEE) countries; however, there are no data regarding clinical phenotypes of these patients in this region. Participation in the Phenotypes of COPD in Central and Eastern Europe (POPE) study was offered to stable patients with COPD in a real-life setting. The primary aim of this study was to assess the prevalence of phenotypes according to predefined criteria. Secondary aims included analysis of differences in symptom load, comorbidities and pharmacological treatment. 3362 patients with COPD were recruited in 10 CEE countries. 63% of the population were nonexacerbators, 20.4% frequent exacerbators with chronic bronchitis, 9.5% frequent exacerbators without chronic bronchitis and 6.9% were classified as asthma-COPD overlap. Differences in the distribution of phenotypes between countries were observed, with the highest heterogeneity observed in the nonexacerbator cohort and the lowest heterogeneity observed in the asthma-COPD cohort. There were statistically significant differences in symptom load, lung function, comorbidities and treatment between these phenotypes. The majority of patients with stable COPD in CEE are nonexacerbators; however, there are distinct differences in surrogates of disease severity and therapy between predefined COPD phenotypes.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30203 - Respiratory systems

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Respiratory Journal

ISSN

0903-1936

e-ISSN

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Volume of the periodical

49

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

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UT code for WoS article

000401788800005

EID of the result in the Scopus database

2-s2.0-85019077682