Wireless Capsule Enteroscopy in Healthy Volunteers

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10329073" target="_blank" >RIV/00179906:_____/16:10329073 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/16:10329073
Result on the web
<a href="https://actamedica.lfhk.cuni.cz/media/pdf/18059694.2016.93.pdf" target="_blank" >https://actamedica.lfhk.cuni.cz/media/pdf/18059694.2016.93.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14712/18059694.2016.93" target="_blank" >10.14712/18059694.2016.93</a>

Result language
angličtina
Original language name
Wireless Capsule Enteroscopy in Healthy Volunteers
Original language description
Introduction: The aim of our prospective study was to define endoscopy appearance of the small bowel in healthy volunteers. Method: Forty-two healthy volunteers underwent wireless capsule endoscopy, clinical investigation, laboratory tests, and completed a health-status questionnaire. All subjects were available for a 36-month clinical follow-up. Results: Eleven subjects (26%) had fully normal endoscopy findings. Remaining 31 persons (74%), being asymptomatic, with normal laboratory results, had some minor findings at wireless capsule endoscopy. Most of those heterogeneous findings were detected in the small intestine (27/31; 87%), like erosions and/or multiple red spots, diminutive polyps and tiny vascular lesions. During a 36-month clinical follow-up, all these 42 healthy volunteers remained asymptomatic, with fully normal laboratory control. Conclusions: Significant part of healthy subjects had abnormal findings at wireless capsule endoscopy. These findings had no clinical relevance, as all these persons remained fully asymptomatic during a 36-month follow-up. Such an endoscopic appearance would be previously evaluated as "pathological". This is a principal report alerting that all findings of any control group of wireless capsule endoscopic studies must be evaluated with caution.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Project
<a href="/en/project/NT13532" target="_blank" >NT13532: Capsule endoscopy in diagnostics of small bowel mucosal injury induced by nonsteroidal anti-inflammatory drugs</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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