Observational Cohort Study of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F17%3A10333329" target="_blank" >RIV/00179906:_____/17:10333329 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/17:10333329

Result on the web

<a href="http://www.scielo.org.mx/pdf/ah/v16n1/1665-2681-ah-16-01-00140.pdf" target="_blank" >http://www.scielo.org.mx/pdf/ah/v16n1/1665-2681-ah-16-01-00140.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5604/16652681.1226932" target="_blank" >10.5604/16652681.1226932</a>

Result language

angličtina

Original language name

Observational Cohort Study of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)

Original language description

INTRODUCTION AND AIM: Hepatic encephalopathy (HE) is a common complication of transjugular intrahepatic portosystemic shunting (TIPS). It is associated with a reduced quality of life and poor prognosis. The aim of this study was to compare two groups of patients who did and did not develop overt HE after TIPS. We looked for differences between these groups before TIPS. MATERIAL AND METHODS: A study of 895 patients was conducted based on a retrospective analysis of clinical data. Data was analyzed using Fisher&apos;s exact test, Chi-square, Mann Whitney test, unpaired t-test and logistic regression. After the initial analyses, we have looked at a regression models for the factors associated with development of HE after TIPS. RESULTS: 257 (37.9%) patients developed HE after TIPS. Patients&apos; age, pre-TIPS portal venous pressure, serum creatinine, aspartate transaminase, albumin, presence of diabetes mellitus and etiology of portal hypertension were statistically significantly associated with the occurrence of HE after TIPS (p &lt; 0.01). However, only the age, pre-TIPS portal venous pressure, serum creatinine, presence of diabetes mellitus and etiology of portal hypertension contributed to the regression model. Patients age, serum creatinine, presence of diabetes mellitus and portal vein pressure formed the model describing development of HE after TIPS for a subgroup of patients with refractory ascites. CONCLUSION: We have identified, using a substantial sample, several factors associated with the development of HE after TIPS. This could be helpful in further research.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30215 - Psychiatry

Project

<a href="/en/project/NS10363" target="_blank" >NS10363: Hemodynamic, clinical and biochemical monitoring of patients before and after transjugular intrahepatic portosystemic shunt (TIPS), part. IV</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Hepatology

ISSN

1665-2681

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

1

Country of publishing house

MX - MEXICO

Number of pages

9

Pages from-to

140-148

UT code for WoS article

000397078000019

EID of the result in the Scopus database

2-s2.0-85007574049