HLö-7 - a review of acetylcholinesterase reactivator against organophosphorous intoxication

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F17%3A10360065" target="_blank" >RIV/00179906:_____/17:10360065 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/17:43889126
Result on the web
<a href="http://mmsl.cz/viCMS/soubory/pdf/MMSL_2017_2_4_WWW.pdf" target="_blank" >http://mmsl.cz/viCMS/soubory/pdf/MMSL_2017_2_4_WWW.pdf</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
HLö-7 - a review of acetylcholinesterase reactivator against organophosphorous intoxication
Original language description
The treatment of organophosphate (OP) poisoning consists of the administration of a parasympatholytic agent, an anticonvulsant and an acetylcholinesterase (AChE) reactivator. Since there is no broad AChE reactivator available, a post-treatment strategy currently exploits administration of different types of oximes depending on the exposure of OP. In this contribution, we summarize all the available data about AChE reactivator HLö-7 including its synthesis, physico-chemical properties, pharmacokinetic and pharmacodynamics profile, and its efficacy in vitro and in vitro.
Czech name
—
Czech description
—

Project
<a href="/en/project/GA15-16701S" target="_blank" >GA15-16701S: Concept of non-quaternary reactivators AChE as the antidotes of organophsophorus poisoning - a new hope or a blind way?</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)