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Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F19%3A10398625" target="_blank" >RIV/00179906:_____/19:10398625 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/19:10398625

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8MVT7uU.oV" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=8MVT7uU.oV</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/14017431.2019.1612088" target="_blank" >10.1080/14017431.2019.1612088</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Female sex as a risk factor in minimally invasive direct coronary artery bypass grafting

  • Original language description

    Objectives. Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. Design. We retrospectively analysed the in-hospital data of all patients (n=384) undergoing MIDCAB at our department in years 2006-2016. Subsequently, the data were enriched by long-term outcomes from national registries. Results. There were 96 women in our group (25%). Females were significantly older (67.1 vs 63.8 years; p&lt;.01) and were more often diabetic (43.8% vs. 31.8%; p&lt;.01). Surgery time was longer in females (160 vs 155min; p=.02), and also the need for blood transfusion (19.8% vs 10.4%; p=.02) and wound complications (15.6% vs 2.4%; p&lt;.001) were more frequent in women. After multivariate analysis, the wound complications risk (p&lt;.001) and longer surgery times (p&lt;.01) remained associated with sex. All-cause in-hospital mortality (2.1% vs 0.7%; p=.26), long-term mortality (p=.73), and the risk of coronary intervention post-operatively (p=.16) were the same in both sexes. Higher incidence of cardiac cause of death in women was observed from long-term aspect (69.6% vs 38.7%; p=.01). However, after adjustment it lost its significance. Conclusions. Female sex is not connected with higher risk of mortality or other major events in MIDCAB. Wound healing complications remain the leading attribute associated with female sex.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scandinavian Cardiovascular Journal

  • ISSN

    1401-7431

  • e-ISSN

  • Volume of the periodical

    53

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    NO - NORWAY

  • Number of pages

    7

  • Pages from-to

    141-147

  • UT code for WoS article

    000476940600005

  • EID of the result in the Scopus database

    2-s2.0-85065673936