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Impact of smoking on the outcomes of minimally invasive direct coronary artery bypass

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10453662" target="_blank" >RIV/00179906:_____/23:10453662 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/23:10453662

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=mUyRvuYO8b" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=mUyRvuYO8b</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s13019-023-02104-9" target="_blank" >10.1186/s13019-023-02104-9</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Impact of smoking on the outcomes of minimally invasive direct coronary artery bypass

  • Original language description

    Background: Tobacco smoking has been associated with an increased risk of complications after conventional coronary surgery. However, the impact of smoking on the risk of postoperative complications in minimally invasive coronary surgery is yet to be studied. We aimed to analyze the impact of the preoperative smoking status on the short- and long-term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in the context of isolated surgical revascularization or in association with percutaneous coronary intervention.Methods: This was a retrospective observational study of all patients undergoing MIDCAB at our institution between 2006 and 2020. Patients were divided into three groups: active smokers, ex-smokers who have quit smoking for atleast 1 month before surgery, and non-smokers. The groups were compared using conventional statistical methods. Multivariate analysis was then performed where signifcant diferences were found to eliminate bias.Results: Throughout the study period, 541 patients underwent MIDCAB, of which 135 (25%) were active smokers, 183 (34%) were ex-smokers, and 223 (41%) were non-smokers. Smokers presented for surgery at a younger age (p&lt;0.0001), more frequently with a history of myocardial infarction (p&lt;0.001), peripheral artery disease (p&lt;0.001) and chronic obstructive pulmonary disease (p&lt;0.0001). Using multivariate analysis, active smoking was determined to be a signifcant risk factor for the need of urgent revascularization (odds ratio 2.36 [1.00-5.56], p=0.049) and thecomposite of pulmonary complications (including pneumothorax, respiratory infection, respiratory dysfunction, subcutaneous emphysema and exacerbation of chronic obstructive pulmonary disease; odds ratio 2.84 [1.64-4.94], p&lt;0.001). Preoperative smoking status did not infuence the long-term survival (p=0.83).Conclusions: In our study, active smokers presented for MIDCAB at a younger age and more often with signs of atherosclerotic disease (history of myocardial infarction and peripheral artery disease). Active smoking was found to be the most signifcant risk factor for postoperative pulmonary complications, and is also associated with a more frequent need for urgent surgery at diagnosis. Long-term postoperative survival is not afected by the preoperative smoking status.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Cardiothoracic Surgery

  • ISSN

    1749-8090

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    1-9

  • UT code for WoS article

    000915653000001

  • EID of the result in the Scopus database

    2-s2.0-85146646882