Acridine derivatives as inhibitors/poisons of topoisomerase II

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F22%3A10442617" target="_blank" >RIV/00179906:_____/22:10442617 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=aBte517Lx6" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=aBte517Lx6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jat.4238" target="_blank" >10.1002/jat.4238</a>

Result language

angličtina

Original language name

Acridine derivatives as inhibitors/poisons of topoisomerase II

Original language description

The potential of acridines (amsacrine) as a topoisomerase II inhibitor or poison was first discovered in 1984, and since then, a considerable number of acridine derivatives have been tested as topoisomerase inhibitors/poisons, containing different substituents on the acridine chromophore. This review will discuss a series of studies published over the course of the last decade, which have investigated various novel acridine derivatives against topoisomerase II activity.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Toxicology

ISSN

0260-437X

e-ISSN

1099-1263

Volume of the periodical

42

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

544-552

UT code for WoS article

000695055000001

EID of the result in the Scopus database

2-s2.0-85114716447