To exploring the role of probiotics, plant-based fermented products, and paraprobiotics as anti-inflammatory agents in promoting human health

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10477530" target="_blank" >RIV/00179906:_____/23:10477530 - isvavai.cz</a>

Alternative codes found

RIV/62690094:18470/23:50020934

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=z-gGcJ.CW7" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=z-gGcJ.CW7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jafr.2023.100896" target="_blank" >10.1016/j.jafr.2023.100896</a>

Result language

angličtina

Original language name

To exploring the role of probiotics, plant-based fermented products, and paraprobiotics as anti-inflammatory agents in promoting human health

Original language description

Inflammation is a complex response to tissue damage and pathogens that can lead to chronic inflammatory disorders and various health complications. Conventional inflammation treatments have limitations, driving the search for alternative approaches. Probiotics have gained attention for their immunomodulatory properties, while paraprobiotics have emerged as a promising anti-inflammatory strategy. Probiotics like Lactobacillus, Bifidobacterium, Saccharomyces, and Bacillus can interact with immune cells through toll-like receptors, triggering the synthesis of anti-inflammatory cytokines and promoting immune cell differentiation. Studies carried out in vivo revealed that TNF- alpha, TRL4, and NF-kappa B were downregulated by Lactobacilli species. In contrast, Bifidobacterium species elevated IL-10 and Foxp3. This helps maintain immune balance and reduce hyperinflammatory responses. Probiotic plant-based fermented products also suppressed NF-kappa B signalling activation and decreased iNOS and COX-2 synthesis. Paraprobiotics, on the other hand, exhibit anti-inflammatory properties and have shown promising results in regulating immune responses and alleviating symptoms in specific inflammatory conditions. They may address concerns related to the viability and safety of live probiotics. This review emphasizes the potential of probiotics, probiotic plant-based fermented products, and paraprobiotics as therapeutic agents for managing inflammatory disorders arising from malnutrition, gut diseases, cardiovascular disease, and neurological disorders. It discusses in-vitro, in-vivo, and human studies highlighting the role of different probiotic strains, commercially available probiotics, challenges with probiotics, probiotic plant-based fermented products, and paraprobiotics in combating inflammation.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Agriculture and Food Research

ISSN

2666-1543

e-ISSN

—

Volume of the periodical

14

Issue of the periodical within the volume

DEC

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

16

Pages from-to

100896

UT code for WoS article

001132653200001

EID of the result in the Scopus database

2-s2.0-85178588840