Recent advances in the concept of paraprobiotics: Nutraceutical/functional properties for promoting children health
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F23%3A50018558" target="_blank" >RIV/62690094:18470/23:50018558 - isvavai.cz</a>
Result on the web
<a href="https://www.tandfonline.com/doi/abs/10.1080/10408398.2021.1996327?journalCode=bfsn20" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/10408398.2021.1996327?journalCode=bfsn20</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10408398.2021.1996327" target="_blank" >10.1080/10408398.2021.1996327</a>
Alternative languages
Result language
angličtina
Original language name
Recent advances in the concept of paraprobiotics: Nutraceutical/functional properties for promoting children health
Original language description
Probiotics consumption has been associated with various health promoting benefits, including disease prevention and even treatment by modulating gut microbiota. Contrary to this, probiotics may also overstimulate the immune system, trigger systemic infections, harmful metabolic activities, and promote gene transfer. In children, the fragile immune system and impaired intestinal barrier may boost the occurrence of adverse effects following probiotics' consumption. To overcome these health challenges, the key focus has been shifted toward non-viable probiotics, also called paraprobiotics. Cell wall polysaccharides, peptidoglycans, surface proteins and teichoic acid present on cell's surface are involved in the interaction of paraprobiotics with the host, ultimately providing health benefits. Among other benefits, paraprobiotics possess the ability to regulate innate and adaptive immunity, exert anti-adhesion, anti-biofilm, anti-hypertensive, anti-inflammatory, antioxidant, anti-proliferative, and antagonistic effects against pathogens, while also enhance clinical impact and general safety when administered in children in comparison to probiotics. Clinical evidence have underlined the paraprobiotics impact in children and young infants against atopic dermatitis, respiratory and gastrointestinal infections, in addition to be useful for immunocompromised individuals. Therefore, this review focuses on probiotics-related issues in children's health and also discusses the Lactobacillus and Bifidobacterium spp. qualities for qualifying as paraprobiotics and their role in promoting the children's health.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21101 - Food and beverages
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Critical Reviews in Food Science and Nutrition
ISSN
1040-8398
e-ISSN
1549-7852
Volume of the periodical
63
Issue of the periodical within the volume
19
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
3943-3958
UT code for WoS article
000715706200001
EID of the result in the Scopus database
2-s2.0-85118626427