Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209775%3A_____%2F10%3A%230000002" target="_blank" >RIV/00209775:_____/10:#0000002 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/10:#0000487 RIV/00216224:14110/10:00051454

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency

Original language description

Patients with generalized bronchiectasis and fibrosis had lower levels of FCRN mRNA compared to patients without these complications. Moreover, FCRN mRNA levels correlated negatively with the extent of bronchiectasis and the rate of IgG decline after infusion of IVIG.Our results showed that FcRn might play a role in the development of lung structural abnormalities and in the catabolism of IVIG in patients with CVID.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/NR9192" target="_blank" >NR9192: Screening of mutations and polymorphisms in neonatal Fc receptor gene in patients with primary disorders of antibody production</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Immunology

ISSN

1521-6616

e-ISSN

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Volume of the periodical

136

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

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UT code for WoS article

000280907000011

EID of the result in the Scopus database

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