Interactions between sleep disordered breathing and atrial fibrillation in patients with hypertrophic cardiomyopathy
Result description
The aim of this study was to investigate whether patients with hypertrophic cardiomyopathy (HC) and sleep-disordered breathing (SBD) have a higher prevalence of atrial fibrillation (AF) compared to patients with HC without SBD. HS is associated with a high prevalence of AF that contributes to increased morbidity and mortality. Overnight oximetry was prospectively performed on 91 consecutive patients with echocardiographically confirmed HC. SBD was associated with a higher prevalence of AF (40% vs 11%, p= 0.005). In addition, SBD was accompanied by significantly increased left atrial volume index (58 +- 19 vs 42 +- 13ml/m2, p = 0.0002). Increasing severity of SBD was correlated with higher AF prevalence and with increase in left atrial volume index. These associations remained significant even after accouting for potential confounders in a multivariete analysis. In conclusion, the presence and severity of SBD may influence left atrial volume index and the prevalence of AF in patients w
Keywords
sleep apnea syndromesatrial fibrillationcardiomyophaty, hypertrophic
The result's identifiers
Result code in IS VaVaI
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Interactions between sleep disordered breathing and atrial fibrillation in patients with hypertrophic cardiomyopathy
Original language description
The aim of this study was to investigate whether patients with hypertrophic cardiomyopathy (HC) and sleep-disordered breathing (SBD) have a higher prevalence of atrial fibrillation (AF) compared to patients with HC without SBD. HS is associated with a high prevalence of AF that contributes to increased morbidity and mortality. Overnight oximetry was prospectively performed on 91 consecutive patients with echocardiographically confirmed HC. SBD was associated with a higher prevalence of AF (40% vs 11%, p= 0.005). In addition, SBD was accompanied by significantly increased left atrial volume index (58 +- 19 vs 42 +- 13ml/m2, p = 0.0002). Increasing severity of SBD was correlated with higher AF prevalence and with increase in left atrial volume index. These associations remained significant even after accouting for potential confounders in a multivariete analysis. In conclusion, the presence and severity of SBD may influence left atrial volume index and the prevalence of AF in patients w
Czech name
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Czech description
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Classification
Type
Jx - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Cardiology
ISSN
0002-9149
e-ISSN
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Volume of the periodical
105
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
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UT code for WoS article
000278475700017
EID of the result in the Scopus database
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Basic information
Result type
Jx - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP
FA - Cardiovascular diseases including cardio-surgery
Year of implementation
2010