Impact of inflammatory infiltration and viral genome presence in myocardium on the changes of echocardiogrraphic parameters
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209775%3A_____%2F13%3A%230000266" target="_blank" >RIV/00209775:_____/13:#0000266 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.crvasa.2013.02.003" target="_blank" >http://dx.doi.org/10.1016/j.crvasa.2013.02.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.crvasa.2013.02.003" target="_blank" >10.1016/j.crvasa.2013.02.003</a>
Alternative languages
Result language
angličtina
Original language name
Impact of inflammatory infiltration and viral genome presence in myocardium on the changes of echocardiogrraphic parameters
Original language description
Seventy patients with a recent occurrence of DCM with left ventricle ejection fraction (LVEF) <40% and with the history of symptoms less than 12 months were enrolled to observation. In EMB samples the average number of T-lymphocytes (CD3+ cells) and mononuclear leucocytes (LCA+ cells) in mm2 was determined. The presence of inflammation was evaluated as positive in case of the findings of >7 CD3+ cells and/or >14 LCA+ cells in mm2. The detection of pathological agents in myocardium was performed by quantitative PCR. According to immunohistological (IH) assessment findings were positive (IH+) in 35 patients (i.e. 50%); thus the inflammatory infiltration was present in myocardium. In remaining patients the findings were negative (IH-). At 6 months follow-up, in the group of IH+ patients the LVEF improved from 25+-9% to 39+-11% and NYHA class declined from 2.8+-0.5 to 1.7+-0.6 (both p<0.001). In IH- group change in LVEF (from 23+-8% to 27+-10%) in contrast to the change of NYHA class (from
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cor et Vasa
ISSN
0010-8650
e-ISSN
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Volume of the periodical
55
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
"E333"-"E340"
UT code for WoS article
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EID of the result in the Scopus database
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