The fourth report of the European registry for patients with mechanical circulatory support (EUROMACS) of the European association for cardiothoracic surgery: focus on standardized outcome ratios

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209775%3A_____%2F25%3AN0000012" target="_blank" >RIV/00209775:_____/25:N0000012 - isvavai.cz</a>

Alternative codes found

RIV/00023001:_____/25:00085429

Result on the web

<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11879288/" target="_blank" >https://pmc.ncbi.nlm.nih.gov/articles/PMC11879288/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/ejcts/ezaf016" target="_blank" >10.1093/ejcts/ezaf016</a>

Result language

angličtina

Original language name

The fourth report of the European registry for patients with mechanical circulatory support (EUROMACS) of the European association for cardiothoracic surgery: focus on standardized outcome ratios

Original language description

Objectives: This 4th report aimed to provide insights into patient characteristics, outcomes and standardized outcome ratios of patients implanted with durable Mechanical Circulatory Support across participating centres in the European Registry for Patients with Mechanical Circulatory Support (EUROMACS) registry.Methods: All registered patients receiving durable mechanical circulatory support up to August 2024 were included. The expected number of events was predicted using penalized logistic regression. Standardized outcome ratios (Observed/Expected events) were presented in plots to assess 30-day and 1-year mortality, ischaemic stroke and major bleeding outcomes. Expected events were estimated using penalized logistic regression using demographics and comorbidities as predictors. Centres with <90% follow-up completeness were excluded from standardized outcome ratio assessment.Results: Analysis included 6962 implants in 6408 patients (457 patients underwent repeated implants) registered in EUROMACS from 17 countries (32 centres) (median age: 58 years, 83% males, 17% Interagency Registry for Mechanically Assisted Circulatory Support class 1). Thirty-day mortality, major bleeding and ischaemic stroke probabilities were 9.6, 12.6% and 2.1%, respectively. Standardized mortality ratios showed variability between centres, ranging from 0 (95% CI 0-0) to 1.4 (95% CI 1.2-1.7). Higher standardized bleeding outcome ratios correlated with higher standardized ischaemic stroke ratio's (Spearman r: 0.56, P = 0.008).Conclusions: Most included centres perform as expected given the demographics and comorbidities of patients. A positive correlation was found between standardized bleeding and ischaemic stroke ratios, reflecting the need of continuously monitoring of adverse events by quality improvement programs.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European journal of cardio-thoracic surgery

ISSN

1010-7940

e-ISSN

1010-7940

Volume of the periodical

67

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

1-9

UT code for WoS article

001437335800001

EID of the result in the Scopus database

2-s2.0-86000139576