A high occurrence of BRCA1 and BRCA2 mutation among czech hereditary breast and breast-ovarian cancer families

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F00%3A00000064" target="_blank" >RIV/00209805:_____/00:00000064 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

A high occurrence of BRCA1 and BRCA2 mutation among czech hereditary breast and breast-ovarian cancer families

Original language description

Molecular genetic testing of BRCA1 and BRCA2 genes in high-risk women with breast/ovarian cancer is effective in determining denetic predisposition to cancer. Spectrum of mutations found in both genes is variable and further investigation is needed for estimation of more frequent or "founder" mutation The genetic counselling and preventive clinical follow-up of gene carriers has to be part of the genetic program.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/NC5561" target="_blank" >NC5561: Mutational analysis of BRCA1 and BRCA2 genes in hereditary forms of breast and ovarian cancer. Clinical application in the South Moravian region.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2000

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Časopis lékařů českých

ISSN

0008-7335

e-ISSN

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Volume of the periodical

139

Issue of the periodical within the volume

20

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

3

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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