Telomeres, telomerase, an immortality

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F12%3A%230000326" target="_blank" >RIV/00209805:_____/12:#0000326 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Telomeres, telomerase, an immortality
Original language description
In 2009, the Nobel Prize in Physiology and Medicine has been awarded to Dr. Elizabeth H. Blackburn, Dr. Carol W. Greider and Dr. Jack W. Szostak ?for the discovery how chromosomes are protected by telomeres and the enzyme telomerase?. A telomere is a region of repetitive nucleotide sequences at the end of the chromosome, which protecs the end of the chromosome from deterioration or from fusion with neighboring chromosomes in eucaryotic cells. A telomerase is an enzyme which adds DNA sequence repeats tothe 3´end of DNA strands in the telomere regions and thus prevents from constant loss of informative DNA from chromosome ends during each replication cycle. Telomerase activity regulation and telomeres deterioration are implicated in various pathophysiological and clinical conditions.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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