Cigarette smoking and lung cancerurelative risk estimates for the major histological types from a pooled analysis of case-control studies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F12%3A%230000356" target="_blank" >RIV/00209805:_____/12:#0000356 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/ijc.27339/abstract;jsessionid=9AE9ABA5F412C1C8DE2F6962F06AB520.d01t01" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/ijc.27339/abstract;jsessionid=9AE9ABA5F412C1C8DE2F6962F06AB520.d01t01</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ijc.27339" target="_blank" >10.1002/ijc.27339</a>
Alternative languages
Result language
angličtina
Original language name
Cigarette smoking and lung cancerurelative risk estimates for the major histological types from a pooled analysis of case-control studies
Original language description
Lung cancer is mainly caused by smoking, but the quantitative relations between smoking and histologic subtypes of lung cancer remain inconclusive. By using one of the largest lung cancer datasets ever assembled, we explored the impact of smoking on risks of the major cell types of lung cancer. This pooled analysis included 13,169 cases and 16,010 controls from Europe and Canada. Studies with population controls comprised 66.5% of the subjects. Adenocarcinoma (AdCa) was the most prevalent subtype in never smokers and in women. Squamous cell carcinoma (SqCC) predominated in male smokers. Age-adjusted odds ratios (ORs) were estimated with logistic regression. ORs were elevated for all metrics of exposure to cigarette smoke and were higher for SqCC and small cell lung cancer (SCLC) than for AdCa. Current male smokers with an average daily dose of >30 cigarettes had ORs of 103.5 (95% confidence interval (CI): 74.8143.2) for SqCC, 111.3 (95% CI: 69.8177.5) for SCLC and 21.9 (95% CI: 16.629.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of cancer
ISSN
0020-7136
e-ISSN
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Volume of the periodical
131
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1210-1219
UT code for WoS article
000305756900049
EID of the result in the Scopus database
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