Cigarette smoking and lung cancer - relative risk estimates for the major histological types from a pooled analysis of case-control studies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12207" target="_blank" >RIV/00216208:11110/12:12207 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/12:10224493

Result on the web

<a href="http://dx.doi.org/10.1002/ijc.27339" target="_blank" >http://dx.doi.org/10.1002/ijc.27339</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cigarette smoking and lung cancer - relative risk estimates for the major histological types from a pooled analysis of case-control studies

Original language description

By using one of the largest lung cancer datasets ever assembled, we explored the impact of smoking on risks of the major cell types of lung cancer. This pooled analysis included 13,169 cases and 16,010 controls from Europe and Canada. Studies with population controls comprised 66.5% of the subjects. Adenocarcinoma (AdCa) was the most prevalent subtype in never smokers and in women. Squamous cell carcinoma (SqCC) predominated in male smokers. Although ORs started to decline soon after quitting, they didnot fully return to the baseline risk of never smokers even 35 years after cessation. The major result that smoking exerted a steeper risk gradient on SqCC and SCLC than on AdCa is in line with previous population data and biological understanding of lung cancer development.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

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Continuities

O - Projekt operacniho programu

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Cancer

ISSN

0020-7136

e-ISSN

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Volume of the periodical

131

Issue of the periodical within the volume

5

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

1210-1219

UT code for WoS article

000305756900049

EID of the result in the Scopus database

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