Genetic variation at the 8q24 locus confers risk to multiple myeloma

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F12%3A%230000359" target="_blank" >RIV/00209805:_____/12:#0000359 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2011.08798.x/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2011.08798.x/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1365-2141.2011.08798.x" target="_blank" >10.1111/j.1365-2141.2011.08798.x</a>

Result language
angličtina
Original language name
Genetic variation at the 8q24 locus confers risk to multiple myeloma
Original language description
Multiple myeloma (MM) is an incurable plasma cell malignancy accounting for 2% of cancer-related deaths worldwide. Ethnic and population variation as well as some evidence of familial clustering indicates a genetic component to myeloma aetiology. We hypothesized that germline variation at the 8q24 locus may affect the risk of acquiring MM. In order to test this hypothesis, we genotyped six single nucleotide polymorphisms (SNPs) in a study of 424 cases and 429 controls. Subjects were recruited from the Epilymph study and the Irish myeloma study.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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