A mini review of organometallic compounds and their anticancer properties

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F13%3A%230000442" target="_blank" >RIV/00209805:_____/13:#0000442 - isvavai.cz</a>

Result on the web

<a href="http://www.mzm.cz/fileadmin/user_upload/publikace/casopisy/fm_49_2_2013/fm-2-2013-abstract-05.pdf" target="_blank" >http://www.mzm.cz/fileadmin/user_upload/publikace/casopisy/fm_49_2_2013/fm-2-2013-abstract-05.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

A mini review of organometallic compounds and their anticancer properties

Original language description

Chemistry of organometallic compounds is a rapidly developing research area. In comparison with purely organic compounds, organometallic compounds show unique chemical properties including structural diversity, variety of available interactions, possibility of ligand exchange and redox and catalytic properties that can be used for medical purposes. The discovery of antitumor properties of cisplatin in 1979 by Rosenberg and its introduction to oncology brought a lot of interest in metal complexes chemistry containing other transition metals. Regardless of severe side-effects and frequent development of tumor resistance, cisplatin, oxaliplatin and carboplatin are still the most successful anticancer compounds. Nevertheless, it is essential to search fornovel anticancer drugs with different modes of action, better selectivity and less side-effects. Organometallic compounds represent a new opportunity to achieve this goal.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Folia Mendeliana

ISSN

0085-0748

e-ISSN

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Volume of the periodical

49

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

53-57

UT code for WoS article

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EID of the result in the Scopus database

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