Circulating miRNAs as new blood-based biomarkers for solid cancers

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F13%3A%230000470" target="_blank" >RIV/00209805:_____/13:#0000470 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/13:00065587

Result on the web

<a href="http://www.futuremedicine.com/doi/abs/10.2217/fon.12.192" target="_blank" >http://www.futuremedicine.com/doi/abs/10.2217/fon.12.192</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2217/FON.12.192" target="_blank" >10.2217/FON.12.192</a>

Result language

angličtina

Original language name

Circulating miRNAs as new blood-based biomarkers for solid cancers

Original language description

miRNAs are short noncoding RNAs that post-transcriptionally regulate gene expression. miRNAs' ability to inhibit translation of oncogenes and tumor suppressor genes implies they have an involvement in carcinogenesis. Specific miRNA expression signatureshave been identified in a variety of human cancers. More recently, occurrence of miRNAs in the blood serum and plasma of humans has been repeatedly observed. miRNA levels in serum and plasma are more stable, reproducible and consistent among individualsof the same species in comparison with other circulating nucleic acids. Circulating miRNAs have been successfully evaluated in a wide range of solid cancers as promising novel noninvasive biomarkers of early disease onset or relapse. Here we describe theorigin of circulating miRNAs, principles of their immense stability and proposed functions, and comprehensively summarize studies focusing on their significance in the most frequently studied cancer types in this regard, including breast

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Future Oncology

ISSN

1479-6694

e-ISSN

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Volume of the periodical

9

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

387-402

UT code for WoS article

000315966900013

EID of the result in the Scopus database

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