Circulating 25-Hydroxyvitamin D-3 and Survival after Diagnosis with Kidney Cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F15%3A00078752" target="_blank" >RIV/00209805:_____/15:00078752 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/15:10297528 RIV/61989592:15110/15:33154945
Result on the web
<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4526455/" target="_blank" >https://pmc.ncbi.nlm.nih.gov/articles/PMC4526455/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1158/1055-9965.EPI-14-1351" target="_blank" >10.1158/1055-9965.EPI-14-1351</a>
Alternative languages
Result language
angličtina
Original language name
Circulating 25-Hydroxyvitamin D-3 and Survival after Diagnosis with Kidney Cancer
Original language description
Prospective cohort studies have provided some evidence that circulating vitamin D is associated with risk of, and survival from, renal cell carcinoma (RCC), but it is unclear whether concentrations of vitamin D at the time of diagnosis of RCC are associated with prognosis. We conducted a case-cohort study of 630 RCC cases, including 203 deaths, from a multicenter case-control study in Eastern Europe. Vitamin D was assessed as 25-hydroxyvitamin D-3 [25(OH)D-3], and we used weighted Cox models to estimate hazard ratios (HR) and 95% confidence intervals (CI) by categories of season-adjusted 25(OH)D-3. Higher concentrations of 25(OH)D-3 were associated with lower risk of death after adjusting for stage, age, sex, and country (HR highest vs. lowest category 0.57; 95% CI, 0.34-0.97). The inverse associations of 25(OH)D-3 with death were most notable among those who died from non-RCC causes and those diagnosed with early-stage disease. In summary, 25(OH)D-3 concentration at diagnosis of RCC was inversely associated with all-cause mortality rates, but not specifically with RCC outcome. (C) 2015 AACR.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30204 - Oncology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cancer epidemiology, biomarkers & prevention
ISSN
1055-9965
e-ISSN
1538-7755
Volume of the periodical
24
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
1277-1281
UT code for WoS article
000359320500018
EID of the result in the Scopus database
2-s2.0-84941775696