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STAT3, stem cells, cancer stem cells and p63

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F18%3A00077980" target="_blank" >RIV/00209805:_____/18:00077980 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863838/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863838/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s11658-018-0078-0" target="_blank" >10.1186/s11658-018-0078-0</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    STAT3, stem cells, cancer stem cells and p63

  • Original language description

    Signal Transducer and Activator of Transcription 3 (STAT3) is a transcription factor with many important functions in the biology of normal and transformed cells. Its regulation is highly complex as it is involved in signaling pathways in many different cell types and under a wide variety of conditions. Besides other functions, STAT3 is an important regulator of normal stem cells and cancer stem cells. p63 which is a member of the p53 protein family is also involved in these functions and is both physically and functionally connected with STAT3. This review summarizes STAT3 function and regulation, its role in stem cell and cancer stem cell properties and highlights recent reports about its relationship to p63.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cellular &amp; molecular biology letters

  • ISSN

    1425-8153

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    22.3.2018

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    20

  • Pages from-to

    12

  • UT code for WoS article

    000428298800001

  • EID of the result in the Scopus database

    2-s2.0-85044297781