Cerebrospinal fluid microRNAs as diagnostic biomarkers in brain tumors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F18%3A00078056" target="_blank" >RIV/00209805:_____/18:00078056 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/18:00105814 RIV/65269705:_____/18:00069233
Result on the web
<a href="https://www.degruyter.com/doi/10.1515/cclm-2017-0958" target="_blank" >https://www.degruyter.com/doi/10.1515/cclm-2017-0958</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/cclm-2017-0958" target="_blank" >10.1515/cclm-2017-0958</a>
Alternative languages
Result language
angličtina
Original language name
Cerebrospinal fluid microRNAs as diagnostic biomarkers in brain tumors
Original language description
Cerebrospinal fluid (CSF) is a body fluid that has many important functions and is in direct contact with the extracellular environment of the central nervous system (CNS). CSF serves as both the communication channel allowing the distribution of various substances among the CNS cells and the storage facility for the waste products these cells release. For these reasons, CSF is a potential source of diagnostic biomarkers of many CNS diseases, including brain tumors. Recent studies have revealed that CSF also contains circulating microRNAs (miRNAs), short non-coding RNAs that have been described as biomarkers in many cancers. However, CSF miRNAs are difficult to detect, which is why researchers face major challenges, including technological difficulties in its detection and its lack of standardization. Therefore, this review aims (i) to highlight the potential of CSF miRNAs as diagnostic, prognostic and predictive biomarkers in brain tumors, and (ii) to summarize technological approaches for detection of CSF miRNAs.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical chemistry and laboratory medicine
ISSN
1434-6621
e-ISSN
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Volume of the periodical
56
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
11
Pages from-to
869-879
UT code for WoS article
000431126000012
EID of the result in the Scopus database
2-s2.0-85042362378