MicroRNA isolation and quantification in cerebrospinal fluid: A comparative methodical study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F18%3A00078109" target="_blank" >RIV/00209805:_____/18:00078109 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/18:00069232 RIV/00216224:14740/18:00106965
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285981/pdf/pone.0208580.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285981/pdf/pone.0208580.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0208580" target="_blank" >10.1371/journal.pone.0208580</a>
Alternative languages
Result language
angličtina
Original language name
MicroRNA isolation and quantification in cerebrospinal fluid: A comparative methodical study
Original language description
Associated with the pathogenesis of many cancers, including brain tumors, microRNAs (miRNAs) present promising diagnostic biomarkers. These molecules have been also studied in cerebrospinal fluid (CSF), showing great potential as a diagnostic tool in patients with brain tumors. Even though there are some biological and technological factors that could affect the results and their biological and clinical interpretation, miRNA analysis in CSF is not fully standardized. This study aims to compare several RNA extraction and miRNA quantification approaches, including high-throughput technologies and individual miRNA detection methods, thereby contributing to the optimization and standardization of quantification of extracellular miRNAs in CSF. Such knowledge is essential for the potential use of miRNAs as diagnostic biomarkers in brain tumors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
<a href="/en/project/NV15-34553A" target="_blank" >NV15-34553A: Usage of cerebrospinal fluid microRNAs in diagnosis of brain tumors</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS ONE [online]
ISSN
1932-6203
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
"e0208580"
UT code for WoS article
000452640900023
EID of the result in the Scopus database
2-s2.0-85058123970