Response to Comparison of Teriparatide and Strontium Ranelate in Postmenopausal Women with Osteoporosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A3962" target="_blank" >RIV/00216208:11110/09:3962 - isvavai.cz</a>

Alternative codes found

RIV/00023728:_____/09:00000097

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Response to Comparison of Teriparatide and Strontium Ranelate in Postmenopausal Women with Osteoporosis

Original language description

The statistically significant reductions compared to baseline in serum PINP and ?-CTx in the SrR group indicate a weak inhibition of bone turnover activity at the dose used in humans and should be taken into account when analyzing the different effects of these two drugs on the bone remodeling cycle using bone biopsies. Changes in microarchitecture induced by SrR in human biopsies cannot be considered as proof of the anabolic effects of this drug, at least at the doses used in humans. These analyses were cross-sectional and not based on paired biopsies. The microstructural differences seen from ?CT of iliac bone biopsies from SrR and placebo treated women were very similar to those described with classical antiresorptives such as alendronate and zoledronate in similar cross-sectional analyses.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Bone and Mineral Research

ISSN

0884-0431

e-ISSN

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Volume of the periodical

24

Issue of the periodical within the volume

12

Country of publishing house

US - UNITED STATES

Number of pages

2

Pages from-to

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UT code for WoS article

000273216600018

EID of the result in the Scopus database

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