Synthesis of unsymmetric cyanine dye via merocyanine and their interaction with DNA

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A4095" target="_blank" >RIV/00216208:11110/09:4095 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/09:4095 RIV/60461373:22340/09:00021843 RIV/68378050:_____/09:00347152

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis of unsymmetric cyanine dye via merocyanine and their interaction with DNA

Original language description

An effective method has been developed for synthesis of neutral merocyanine dye 4 from (4-nitrophenyl)malondialdehyde. Merocyanine 4 was used as a basic building block for preparation of unsymmetric cyanine dyes 9 and 10, both derived from the same aromatic malondialdehyde. With the cyanine 10, pH-dependent affinity to DNA has been studied. Unsymmetric cyanine dye 10 has been compared with symmetric dye 8. The corresponding binding constants (K) have been calculated for various pH.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Collection of Czechoslovak Chemical Communications

ISSN

0010-0765

e-ISSN

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Volume of the periodical

74

Issue of the periodical within the volume

7-8

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

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UT code for WoS article

000269891900005

EID of the result in the Scopus database

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