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Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F24%3A10483681" target="_blank" >RIV/00216208:11110/24:10483681 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/24:00136836 RIV/00064165:_____/24:10483681

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9hjXeYTufJ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=9hjXeYTufJ</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s42004-024-01256-6" target="_blank" >10.1038/s42004-024-01256-6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

  • Original language description

    Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other hand, its destabilization strongly represses the viability and metastatic potential of cancer cells. Photodynamic and photothermal therapies (PDT and PTT) target mitochondria effectively, providing innovative and non-invasive anticancer therapeutic modalities. Cyanine dyes, with strong mitochondrial selectivity, show significant potential in enhancing PDT and PTT. The potential and limitations of cyanine dyes for mitochondrial PDT and PTT are discussed, along with their applications in combination therapies, theranostic techniques, and optimal delivery systems. Additionally, novel approaches for sonodynamic therapy using photoactive cyanine dyes are presented, highlighting advances in cancer treatment. Photodynamic and photothermal therapies (PDT and PTT) target mitochondria effectively, providing innovative and non-invasive anticancer therapeutic modalities. Here, the authors summarize the promise and limitations of cyanine dyes in enhancing mitochondrial PDT and PTT in cancer treatment.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Communications Chemistry

  • ISSN

    2399-3669

  • e-ISSN

    2399-3669

  • Volume of the periodical

    7

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    39

  • Pages from-to

    180

  • UT code for WoS article

    001290265400001

  • EID of the result in the Scopus database

    2-s2.0-85201254968